Seronegative Arthritis Definition

Seronegative arthritis is an inflammatory arthritis in which antibodies usually present are missing from the blood, making it difficult to diagnose a specific rheumatic condition, such as rheumatoid arthritis or lupus. Once time has passed and other diagnoses can be ruled out, this condition is typically diagnosed as rheumatoid arthritis.

Palmar view of a hand with rheumatoid arthritis in the joints.