Still's Disease Definition

Juvenile rheumatoid arthritis (JRA) is one of the most common chronic diseases of childhood, representing a large grouping of disorders that all present with chronic joint inflammation. The origin of the disease is complex, involving a strong genetic component and an external trigger (such as infection or trauma) that triggers an autoimmune reaction and subsequent joint pain and inflammation. The varied possibility of influences makes specific diagnosis of JRA very difficult.

Anterior view of a skeleton highlighting rheumatoid arthritis in symmetrical joints.