For some people with rheumatoid arthritis, chronic fatigue can be more debilitating than the painful, swollen joints associated with the disease.1 Experts estimate than anywhere from 40% to nearly 90% of RA patients experience chronic fatigue.2-4
Rheumatoid Arthritis Fatigue Is Different Than Just Being Tired
The fatigue associated with rheumatoid arthritis has been compared to the fatigue typically experienced by patients with cancer. RA fatigue may be characterized as:5
- Abnormal, excessive whole-body exhaustion
- Physical tiredness or weakness not related to exercise or exertion
- Lasting for more than a month
- Not easily relieved by sleep or rest
In addition to feeling tired, people with chronic fatigue may experience:
- More pain. Patients who are fatigued have a more difficult time coping with pain, and pain may seem worse.
- An inability to concentrate. Chronic fatigue can affect people both physically and mentally, and critical thinking and decision-making may take longer and seem more difficult.
- Helplessness. People can feel like they are losing control of their lives because they are physically and mentally exhausted.
- Irritability. Patients who are fatigued face constant mental and physical challenges throughout the day leading to moodiness and irritability.
Chronic fatigue can lead to feelings of helplessness and irritability as well as depression.
Fatigue Is Associated With Depression
The association between depression and fatigue is not surprising, given that people living with chronic fatigue may feel unable to keep up with their work, household responsibilities, and relationships. Also, because bouts of fatigue are unpredictable, people with rheumatoid arthritis may have difficulty planning ahead for events, such as home projects or vacations. Cancelling or missing out on normal activities is frustrating and can make a person feel unproductive and isolated.
Depression is not the only mood disorder associated with rheumatoid arthritis. One study found that anxiety is at least as common as depression among people diagnosed with rheumatoid arthritis.8
When fatigue is significantly reduced, a person with RA has more energy to do chores around the house,9 exercise, and socialize, which in turn can help alleviate feelings of depression.