Knowing the underlying cause of shoulder arthritis may help guide treatment recommendations. Many risk factors exist, and evidence suggests the most significant are a previous shoulder injury or overuse.1Macías-Hernández SI, Morones-Alba JD, Miranda-Duarte A, et al. Glenohumeral osteoarthritis: overview, therapy, and rehabilitation. Disabil Rehabil. 2017 Aug;39(16):1674-1682. doi: 10.1080/09638288.2016.1207206. Epub 2016 Jul 14. Review. PubMed PMID: 27416338.

Risk Factors for Shoulder Arthritis

Experts estimate 90% of people who have shoulder arthritis have one or more risk factors.2Oh JH, Chung SW, Oh CH, et al. The prevalence of shoulder osteoarthritis in the elderly Korean population: association [33] with risk factors and function. J Shoulder Elbow Surg. 2011;20:756–763. As cited in Macías-Hernández SI, Morones-Alba JD, Miranda-Duarte A, et al. Glenohumeral osteoarthritis: overview, therapy, and rehabilitation. Disabil Rehabil. 2017 Aug;39(16):1674-1682. doi: 10.1080/09638288.2016.1207206. Epub 2016 Jul 14. Review. PubMed PMID: 27416338.,3Rozencwaig R, van Noort A, Moskal MJ 3rd, et al. The correl- [35] ation of comorbidity with function of the shoulder and health status of patients who have glenohumeral degenerative joint disease. J Bone Joint Surg Am. 1998;80:1146–1153. As cited in acías-Hernández SI, Morones-Alba JD, Miranda-Duarte A, et al. Glenohumeral osteoarthritis: overview, therapy, and rehabilitation. Disabil Rehabil. 2017 Aug;39(16):1674-1682. doi: 10.1080/09638288.2016.1207206. Epub 2016 Jul 14. Review. PubMed PMID: 27416338. Possible risk factors include:

  • Shoulder joint injury. A broken bone, dislocation (when the humeral head pops out of its socket), or other serious trauma or surgery can cause damage to the shoulder joint. The damage can eventually lead to shoulder osteoarthritis. Symptoms may not appear until years after the trauma.
  • Shoulder joint stress and chronic injury. People whose jobs or recreational lifestyle require spending a lot of time lifting objects overhead, throwing, or doing high-impact activities—such as chopping wood or using an air-hammer—can experience “mini-traumas” in their shoulder joints. These mini-traumas increase the risk of developing shoulder osteoarthritis.
  • Advanced age. Shoulder arthritis most commonly affects people over the age of 50.4Burbank KM, Stevenson JH, Czarnecki GR, et al. Chronic [31] shoulder pain: part I. Evaluation and diagnosis. Am Fam Physician. 2008;77:453–460. As cited in Macías-Hernández SI, Morones-Alba JD, Miranda-Duarte A, et al. Glenohumeral osteoarthritis: overview, therapy, and rehabilitation. Disabil Rehabil. 2017 Aug;39(16):1674-1682. doi: 10.1080/09638288.2016.1207206. Epub 2016 Jul 14. Review. PubMed PMID: 27416338. The prevalence of symptomatic osteoarthritis increases with age because, over time, the shoulder joints experience wear and tear that can cause cartilage to thin and becomes less flexible.
  • Congenital defect. Poor bone alignment, which also makes some people more likely to suffer shoulder dislocations, can increase the risk of developing shoulder osteoarthritis.
  • Autoimmune arthritis or other illness. Autoimmune arthritis, such as rheumatoid arthritis, or a history of gout, septic arthritis, or other metabolic disorder can increase the risk of shoulder osteoarthritis.
  • Gender. Glenohumeral arthritis is more common in women.
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  • Obesity. While the shoulder is not a weight-bearing joint, research suggests that people who are overweight are more likely to get shoulder arthritis.1Macías-Hernández SI, Morones-Alba JD, Miranda-Duarte A, et al. Glenohumeral osteoarthritis: overview, therapy, and rehabilitation. Disabil Rehabil. 2017 Aug;39(16):1674-1682. doi: 10.1080/09638288.2016.1207206. Epub 2016 Jul 14. Review. PubMed PMID: 27416338. Obesity is associated with low-grade, systemic (body-wide) inflammation, which may contribute to the development of osteoarthritis.5Sartori-Cintra AR, Aikawa P, Cintra DE. Obesity versus osteoarthritis: beyond the mechanical overload. Einstein (Sao Paulo). 2014;12(3):374–379. doi:10.1590/S1679-45082014RB2912.,6Rosen, C.J. Pathogenic mechanisms of obesity-induced osteoarthritis: new clues from old joints Osteoarthritis and Cartilage. April 2019. Volume 27, S15. DOI: https://doi.org/10.1016/j.joca.2019.02.007 (Obesity is defined as a BMI ≥ 30.)
  • Genetics. Similar to height and hair color, the likelihood of a person developing shoulder osteoarthritis is influenced by genetics. While the exact extent of genetic factors is not known, a woman whose mother has shoulder osteoarthritis is more likely to develop the disease than another woman whose mother did not have shoulder osteoarthritis.
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It is possible for a person without any of the above risk factors to develop the shoulder arthritis. Likewise, a person with all of the above characteristics may never develop it.

  • 1 Macías-Hernández SI, Morones-Alba JD, Miranda-Duarte A, et al. Glenohumeral osteoarthritis: overview, therapy, and rehabilitation. Disabil Rehabil. 2017 Aug;39(16):1674-1682. doi: 10.1080/09638288.2016.1207206. Epub 2016 Jul 14. Review. PubMed PMID: 27416338.
  • 2 Oh JH, Chung SW, Oh CH, et al. The prevalence of shoulder osteoarthritis in the elderly Korean population: association [33] with risk factors and function. J Shoulder Elbow Surg. 2011;20:756–763. As cited in Macías-Hernández SI, Morones-Alba JD, Miranda-Duarte A, et al. Glenohumeral osteoarthritis: overview, therapy, and rehabilitation. Disabil Rehabil. 2017 Aug;39(16):1674-1682. doi: 10.1080/09638288.2016.1207206. Epub 2016 Jul 14. Review. PubMed PMID: 27416338.
  • 3 Rozencwaig R, van Noort A, Moskal MJ 3rd, et al. The correl- [35] ation of comorbidity with function of the shoulder and health status of patients who have glenohumeral degenerative joint disease. J Bone Joint Surg Am. 1998;80:1146–1153. As cited in acías-Hernández SI, Morones-Alba JD, Miranda-Duarte A, et al. Glenohumeral osteoarthritis: overview, therapy, and rehabilitation. Disabil Rehabil. 2017 Aug;39(16):1674-1682. doi: 10.1080/09638288.2016.1207206. Epub 2016 Jul 14. Review. PubMed PMID: 27416338.
  • 4 Burbank KM, Stevenson JH, Czarnecki GR, et al. Chronic [31] shoulder pain: part I. Evaluation and diagnosis. Am Fam Physician. 2008;77:453–460. As cited in Macías-Hernández SI, Morones-Alba JD, Miranda-Duarte A, et al. Glenohumeral osteoarthritis: overview, therapy, and rehabilitation. Disabil Rehabil. 2017 Aug;39(16):1674-1682. doi: 10.1080/09638288.2016.1207206. Epub 2016 Jul 14. Review. PubMed PMID: 27416338.
  • 5 Sartori-Cintra AR, Aikawa P, Cintra DE. Obesity versus osteoarthritis: beyond the mechanical overload. Einstein (Sao Paulo). 2014;12(3):374–379. doi:10.1590/S1679-45082014RB2912.
  • 6 Rosen, C.J. Pathogenic mechanisms of obesity-induced osteoarthritis: new clues from old joints Osteoarthritis and Cartilage. April 2019. Volume 27, S15. DOI: https://doi.org/10.1016/j.joca.2019.02.007

Dr. Ana Bracilovic is a physiatrist at the Princeton Spine and Joint Center, where she has more than a decade of experience specializing in the diagnosis and non-surgical treatment of spine, joint, and muscle pain.

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